Thakor Lab YouTube page
 
 
 
Teaching
 580.470 Biomedical Instrumentation II: Molecules & Cells
Course Overview
This core design course is tailored to explore the fundamentals of molecular and cellular measurements, related technologies and their applications in scientific research. The course will include a guided lab and challenging hands-on group projects. Emphasis will be on prevalent microtechnologies applied to developing instrumentation capable of handling cells and biological molecules, their manipulation, detection and measurements. The course will also involve a term paper consisting of a literature review on such technology. Students will research specialized instrumentation and present this in class.
 
Course Administration
Instructor Dr. Nitish Thakor
Dr. Leslie Tung
nitish@jhu.edu
ltung@jhu.edu
Teaching
Assistants
Rezina Siddique rsiddiq2@jhmi.edu
Project Mentors Suneil Hosmane, Abhishek Rege, Kartikeya Murari
Timings Lecture Timings:
Lab Timings:
TA Office Hours:
4:00pm - 5:15pm on Thursdays
1:00pm - 3:00pm on Fridays
TBD
Location Lectures:
Labs:
Barton Hall 114
Clark Hall 119 (unless otherwise stated)
Grading Labs & Assignments
Student Presentations & Term Paper
Final Project
50%
20%

30%

Lecture Notes
Lecture 1 Molecules and Cells (Thakor)
Lecture 2 Microfabrication (Hosmane)
Lecture 3 Microfluidics (Rege)
Lecture 4 Fluidics in vitro Studies (Thakor)
Lecture 5 Biosensors (Thakor)
Lecture 6 Bioelectricity (Tung)
Lecture 7 Molecular Sensing (Thakor)
Lecture 8 Cellular Sensing (Tung)
Lecture 9 Advanced Microfabrication (Gracias)
Lecture 10 MicroBio Systems (Thakor)
Lecture 11 NanoBio Systems (Mao)
 
Labs
Lab 1 Mask Design for Photolithography (Microfab Lab)
Lab 2 Template Making with Lithography (Microfab Lab)
Lab 3 Microfluidic Devices with PDMS (Microfab Lab)
Lab 4 Simulation of Microfluidic Applications (HAC Lab)
Lab 5 Testing Microfluidic Devices (Microfab Lab)
Lab 6 Cell/Particle Counters (Instrumentation Lab)
Note that while entering the lab every week, the student is required to hand over to the TAs:
  
  • Answers to the pre-lab questions for that particular lab
  •   
  • Answers to the post-lab questions for the previous lab
  •  
    Assignments
    Assignment 1 Mask Design
    Assignment 2 Microfluidics for Biomedical Applications
     
    Projects
    Project 1 Christmas Tree Gradient Generator for Cell Differentiation Study
    Project 2 Electrochemical Sensors for Biomolecules
    Project 3 On-Stage Incubator for Long Term Cell Studies
    Project 4 Self Assembled Monolayers (SAMs) for Time-Controlled Desorption
    Project 5 Cell Tracking for Motile Cells or Cellular Processes
     
    Textbook/Reading
    Microfabrication  Marc Madou, Fundamentals of Microfabrication, CRC Press.
    Microfluidics  Ch 1‒5 of Streeter and Wylie, Fluid Mechanics, McGraw-Hill, 1998
    Imaging  Online content by Nikon: http://www.microscopyu.com/sitemap.html
     
     
     
       

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