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 580.471 Biomedical Instrumentation I: Signals & Systems
Course Overview
This core design course will cover fundamentals of biomedical sensors and instrumentation, FDA regulations, designing with electronics, biopotentials and ECG amplifier design, recording from heart, muscle, brain, etc., diagnostic and therapeutic devices (including pacemakers and defibrillators), applications in prosthetics and rehabilitation, and safety. The course includes extensive laboratory work involving circuits, electronics, sensor design and interface, and building complete biomedical instrumentation. The students will also carry out design challenge projects, individually or in teams (examples include "smart cane for blind", "computer interface for quadriplegic", etc.)
Course Administration
Instructor Dr. Nitish Thakor
Jim Gwilliam
Xiaoxu Kang
Janaka Senarathna
Dan Wu
Timings Lecture Timings:
Lab Timings:

TA Office Hours:
4:00pm - 6:00pm on Thursdays
9:00am - 12:00pm on Fridays (Section 1)
1:00pm - 4:00pm on Fridays (Section 2)
Thursday 6:00pm onwards in Hodson Hall
Location Lectures:
Hodson Hall
Clark Hall 221 (Instrumentation Lab)
Grading Labs
Challenge Project
eHT, i4GH Term Paper

Lecture Notes
Lecture 1 Introduction and Safety
Lecture 2 Circuits and Electronics
Lecture 3 Integrated Electronics and Biopotential Measurements
Lecture 4 Origin of Biopotentials
Lecture 5 Sensors
Lecture 7 Electrodes
Lecture 8 Therapeutic Cardiovascular Devices
Lecture 9 Neural Devices and Systems
Lab 1 Operational Amplifiers and Filters
Lab 2 Differential and Instrumentation Amplifiers
Lab 3 ECG and EMG Amplifiers
Lab 4 Programmable Microcontrollers
Lab 5 Application of Sensors
Lab 6 RS-232 and Wireless Communication
Note that while entering the lab every week, the student is required to hand over to the TAs:
  • Answers to the pre-lab questions for that particular lab
  • Answers to the post-lab questions for the previous lab
    Timely assignments will be given out in the lectures. Assignments typically include design problems based on what is taught in class.

    Challenge Project
    This is an extension of the labs, when students in teams of two or three, will take on a more involved and challenging project and compete against other teams in a challenge project competition. Previous challenge projects have included "who types a message the fastest using a self designed quadriplegic keyboard" or "who best navigates through an obstruction maze using a self designed blind man's SMART cane". The TAs along with Dr. Thakor will decide the challenge project for this year and inform the students well in time. This typically requires about four Fridays of lab-time and burning some midnight oil to get things to work before the deadlines. The toil and eventual achievement is usually enjoyed by the students.

    Challenge Project 2008

    John G. Webster, Medical Instrumentation, 3rd Ed, John Wiley & Sons, 1998

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