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 585.408.31 Biomedical Instrumentation for APL
Course Overview
This course covers the basic and advanced principles, concepts, and operations of medical sensors and devices. The origin and nature of measurable physiological signals are studied, including chemical, electrochemical, optical, and electromagnetic signals. The principles and devices to make the measurements, including design of electronic instrumentation, will be rigorously presented. This will be followed by realistic design and experimentation with amplifiers for biopotential measurements. Finally, therapeutic instrumentation such as pacemakers, defibrillators and prosthetic devices will be reviewed. There will be 4 laboratories to give students hands on experience with electronic components, sensors, biopotential measurements and testing therapeutic instrumentation. The final part of this course will cover emerging frontiers of cellular and molecular instrumentation.
Course Administration
Instructor Dr. Nitish Thakor
Gracee Agrawal
Xiaoxu Kang
Jai Madhok
Timings Lecture Timings:
Lab Timings:
4:00pm - 5:30pm on Wednesdays
9:00am - 1:00pm on Saturdays (4 labs)
Location Lectures:
Applied Physics Laboratory (APL)
Clark Hall 221 (Instrumentation Lab)
Grading Take-Home Assignments
In-Class Problems (5)
Labs (4)

Lecture Notes
Lecture 1a Introduction
Lecture 1b Electrical Safety
Lecture 2 Origins of Biopotentials
Lecture 3 Circuits and Electronics
Lecture 4 Integrated Electronics
Lecture 5 Biopotential Measurements
Lecture 6 Sensors
Lecture 7 Electrodes
Lecture 8 Therapeutic Cardiovascular Devices
Lecture 9 Neural Devices and Systems
Lecture 10 MEMS
Lecture 11 Cellular Instrumentation
Lecture 12 Molecular Instrumentation
Lab 1 Basic Circuits: Opamps, Filters,Amplifiers
Lab 2 Sensors
Lab 3 Biopotentials
Lab 4 Prosthetic Devices
Note that while entering the lab every week, the student is required to hand over to the TAs:
  • Answers to the pre-lab questions for that particular lab
  • Answers to the post-lab questions for the previous lab
    Timely assignments will be given out in the lectures. Assignments typically include design problems based on what is taught in class.

    This will include the student's review of what is out there (state of the art) in a specific medical technology. An example of a term paper topic is "Use of dielectrophoresis in biomedical instrumentation". The student will be required to formulate the theory for dielectrophoresis and how it is used for biomedical instrumentation (concepts of basic application). The student will further review some cutting edge papers and patents and include such example applications and conclusions in his/her report. Extra credit will be given, if improvements or ideas are suggested.

    The reports and presentations will be graded for:

  • Organization: clarity, content, and with historic background & contemporariness
  • Research: cutting edge products (with concepts), companies & applications
  • Citations: quality of references, including figures, contacts/initiative

  • Textbook/Reading
    John G. Webster, Medical Instrumentation, 3rd Ed, John Wiley & Sons, 1998

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    All rights reserved.