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VLSI & Instrumentation
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Simultaneous detection and sensing of neurochemicals and electrophysiological field potentials is potentially useful in studying the interaction between chemical synaptic activity and electrical neuronal activity. At insulating gaps between two neurons (the synapse), the electrical activity in the pre-synaptic neuron causes the release of neurotransmitters into the synaptic cleft. Post-synaptic neurons sense these neurotransmitters, and based on the specific chemical message, initiate or suppress the transmission of electrical activity through them. To be able to monitor these related signals in vivo is even more useful as it allows continuous sensing from awake and behaving animals. This could provide important information regarding neurologicalconditions where there is an imbalance between the chemical and electrical activity like epilepsy.
Over the years, our group has designed several VLSI systems for monitoring different modalities of neural signals including:
16-channel Potentiostat
16-channel Neuropotential Monitoring
Head-mounted Imager
RF Telemetry and Power Harvesting
Additionally, we have designed a system to interface all these modules. We are planning to wirelessly monitor EEG and dopamine activity from awake behaving rats following cardiac arrest.
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